The star has passed away following a heart attack, according to the Miami Herald.
Mechoso had a lengthy career in TV, appearing in The Big Bang Theory and Grey’s Anatomy, as well as Seinfeld and Miami Vice.
He also starred in films including The Legend of Zorro, Jurassic Park III and Little Miss Sunshine.
Mechoso’s old friend and fellow actor Andy Garcia, paid an emotional tribute to Mechoso following his passing.
According to the Miami Herald, he wrote in a letter: “How can one express the extreme loss of someone so close to you, the extreme emptiness that one feels now and forever.
“A sudden loss is always unjust, but in the case of Julio Oscar Mechoso, my friend, my soul mate it is greater than that, as I have lost the truest of friends.”
Antonio Carluccio has died, aged 80, on November 8 [Getty]
“Julio is a unique and extraordinary artist. I say is, because his artistry will carry on and will be present in all that will witness it.
“I will miss you, my brother. You left us an incredible and inspirational body of work.
“I will carry on, as you would like me to. As it is our duty. With you always by my side. Cherishing the work, and honoring your spirit in my work. That is my promise to you.”
Mechoso also regularly worked with director Robert Rodriguez, including movies Once Upon a Time in Mexico, Planet Terror, Grindhouse and Machete Kills.