The EU poster boy’s remarks came as he unveiled a plot to make French the world’s most commonly spoken language in the bloc.
Emmanuel Macron said: “The situation now is quite paradoxical. English has probably never been as present in Brussels at the time when we are talking about Brexit.
“This domination is not inevitable. It’s up to us to set some rules, to be present, and make French the language with whom one has access to a number of opportunities.”
French has long been dominant at EU headquarters and there are some 274 million French speakers worldwide, making it the fifth most widely spoken language in the world.
But since eastern European members joined the Brussels club in 2004, English has become far-reaching across EU institutions.
Mr Macron insisted his plot is not against the use of English, but more to promote multilingualism.
The Frenchmen set out a plan to spend hundreds of millions of Euros to promote the French language in Africa’s countries with the fastest growing populations last November while visiting Burkina Faso.
However, since the announcement he has faced a string of backlash, with accusations of the leader trying to suppress native cultures in favour of French.
EU chief Jean-Claude Juncker also waded into the debate by backing Mr Macron’s plan because he is a “enthusiastic backer of multilingualism”.
He told France 5 TV channel: “Why would Shakespeare’s language be superior to that of Voltaire?
“We are wrong to have become so anglicised.”
But Mr Juncker added: “ English has become a daily working language wishing the EU institutions. Brexit won’t change anything to it.
“Because those who don’t come from the western part of Europe have become used to speaking in English.”