Europhile Gianni Pittella, an MEP for centre-left wing Democratic Party (PD), admitted the defeat of traditional politics in Italy and Europe.
Speaking at an event organised by the Progressive Alliance of Socialists and Democrats in the European Parliament, he said the latest wave of populism and new political breakthrough such as Brexit have unearthed the shortcomings of traditional politics.
Mr Pitella said: “Brexit, the decline of European historical parties, the difficulties of the European Union and all the other political and social phenomena are not elements emerging randomly, but a representation of the end of a political order.”
Arguing that what politics is lacking today is “an idea of the future”, he called for “new answers” to tackle the “phase of quick changes” the world is living.
He added: “We need to find new answers, which are not the sly and superficial overcoming of the right and left wing politics, or the ecumenism put forward by new Prime Minister Giuseppe Conte, but politically clear answers that combine environmentalism, socialism, Europeanism, democracy, rights and equality.
“What we need to make these ideas appealing to the future without incite hate or cultural barriers.”
The warning has been issued a week after a populist government has sworn in for the first time in the history of the Italian Republic.
On June 1, the newly-formed Lega-Five Star Movement coalition pledged to respect the Italian Constitution after more than 80 days of political deadlock following the March 4 elections.
The new anti-establishment government, led by Prime Minister Giuseppe Conte, looks set to destabilise the already fragile equilibrium of the EU.
Including two eurosceptic personalities, Lega’s Matteo Salvini and Luigi Di Maio’s Five Star, the government has promised to make costly changes in Italy, including the introduction of a flat tax, and change its immigration policy.
This could put Italy, the third-largest economy in the eurozone, on a collision course with the bloc.
And the EU is already facing problems with the UK over the Brexit deal.
On Wednesday, Theresa May introduced a backstop plan to avoid the creation of an hard border between Northern Ireland and the Republic of Ireland, but EU Chief Negotiator Michel Barnier rebutted it.
(Additional reporting by Maria Ortega)